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While clinical studies using NAD-boosters, glutathione or NAC in different diseases are increasing in number, their implementation as trial end-points and in clinical use is hampered by the lack of knowledge of their ranges in healthy population, especially in the blood, an accessible sample source

The 8-oxo-dG adduct in the mitochondrial and nuclear DNA is a pre-mutagenic lesion formed primarily by an attack by the hydroxyl radical ( OH)

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122 Extensive research on post-translational protein modifications has led to the discovery of new modification modes, such as histone tyrosine sulfation