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For instance, post-hoc analyses of pre- and post-treatment biopsy samples from Ewing sarcoma patients treated with either IGF-1R mAb or a combination of cixutumumab and the mTOR inhibitor temsirolimus revealed that median PFS and OS was better in phospho-IGF-1R-negative patients

PLoS One , 8 (8), e69515

This reduction in BCAAs disrupts the plasma BCAA/AAA ratio, which promotes the influx of AAAs across the blood-brain barrier

Mamm Genome 22(56):261271

Alternative mechanisms of action of metallic nanoparticles to mitigate the global spread of antibiotic-resistant bacteria

2017 Apr;19(4):33
