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Gastroenterology 144, 5961.e6
Cunningham et al have worked on the delivery of OTC through an adeno-associated virus 2/8 vector in OCTD mouse model (spf ash mouse models)
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Furthermore, in aged mice treated with lipopolysaccharide to increase BBB permeability, melatonin-activated AMP-activated protein kinase in endothelial cells of the BBB [197], a kinase essential for maintaining BBB integrity [198]
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