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Aside from its feel good function, dopamine is involved in many body functions

Substrate is shown in yellow, GS in green and residues C/S13, V12 and the backbone of A11 in magenta

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However, the transient interaction with IgM is sufficient to deposit sublytic quantities of C3b, an excellent opsonin, which leads to the removal of red cells by phagocytes in the spleen, liver, and bone marrow (extravascular hemolysis)

Arch Gen Psychiatry 1998

Results showed that the PDO response to treatment predicted patient outcomes with 88% accuracy (Vlachogiannis et al., 2018)