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doi: 10.1002/med.21599 135 CostaEDRezendeBACortesSFLemosVS

Given the wide availability of anti-RA drugs that only prove effective after several cycles, prior individualized target screening to guide treatment choice, particularly through aOoC technology, would enable faster and more precise evaluation of therapeutic response and support a more personalized approach to disease management

PPARa contributes to neuronal ferroptosis by regulating the FSP1-CoQ10-NAD(P)H pathway through its transcriptional activity To elucidate the specific mechanism by which PPARa regulates FSP1, we constructed stable cell lines with either over-expression or knockdown of PPARa using lentiviral vectors

Cicero, A

CDK4/6-inhibiting drug substitutes for p21 and p16 in senescence: duration of cell cycle arrest and MTOR activity determine geroconversion
