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Catalyzed by glutathione synthetase ( GSS ), this step is generally not rate-limiting under normal conditions but GSS variants that reduce enzyme activity can become limiting when step 1 is driving high -GluCys throughput, or when glycine availability is restricted
They must manage the oxidative stress conditions that are marked by heightened ROS concentrations (125)

S9a, b)

IV should be medically supervised

10-12 Therefore, lifestyle modification is critical to polycystic ovary syndrome management