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Supplemental Figure 3E)
[DOI] [PubMed] [Google Scholar] 51.Molfino A., Cascino A., Conte C., Ramaccini C., Rossi Fanelli F., Laviano A
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The rationale for adding it to tirzepatide is that calorie restriction and GI side effects from GLP-1 medications can reduce B12 absorption, potentially leading to deficiency over time
Relative quantification was performed by normalizing the sum of the AUC of all isotopologues for each metabolite to the sum of the AUC of all isotopologues of norvaline within each sample followed by normalization to the average protein quantification within each experimental group
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