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Many athletes use IGF-1 for its anabolic effect in muscle and to facilitate the development of cartilage and bone
It can modulate sleep and wake functions

Molecules and cells

Genetic polymorphisms in the endothelial nitric oxide synthase gene correlate with overall survival in advanced non-small-cell lung cancer patients treated with platinum-based doublet chemotherapy

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Though human studies are lacking, preclinical trials support its potential in treating fractures
