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All expression constructs were validated by DNA sequencing

The study found that RK could inhibit the expression of adipogenic and lipogenic genes as well as enhance the expression of genes involved in lipolysis and fatty acid oxidation pathways

Nov 17 2009;106(46):19432-7

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This residue and F135 on TM2 are shown as they are located where the substrate entry from the membrane is expected

10.1016/j.molcel.2021.08.018 61 LevineB.KroemerG
