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For example, take your multivitamin with breakfast and your calcium supplements with lunch to prevent calcium from affecting the absorption of other minerals such as iron, magnesium, copper, and zinc in the multivitamin

[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Brown TM, Tsujimura S-I, Allen AE, et al

Bidirectional communication between the ENS and the CNS, the gut-brain axis, integrates digestive and defensive functions of the gut with those of other organs to maintain homeostasis (710) (FIGURE 1)

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People at highest risk include those with pernicious anaemia, strict vegans and vegetarians, individuals over 60, patients with gastrointestinal disorders (Crohn's disease, coeliac disease), those who have had gastric or bariatric surgery, and long-term users of metformin or proton pump inhibitors