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Description
Transcriptional regulatory axis of HER2-ELF3-KRAS as a therapeutic target for KRAS G13D CRCs G13D Building on our findings that HER2 is a predictive biomarker and prognostic factor for CTX response in KRAS G13D CRCs, we investigated potential strategies to regulate HER2 as a novel therapeutic approach for CRC patients harboring the KRAS G13D mutation
We investigated whether NAM regulates the activity of FOXO3A by using the FOXO3A reporter plasmid FHRE-Luc

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In mice pre-fed MPs, cyclophosphamide administration caused a more pronounced hepatotoxic effect compared to those without MPs in the diet

Some cancer cells resist conventional therapies due to apoptosis deficiencies, rendering them resistant to elimination

In addition to the VM-M3 tumour, we also evaluated the effects of the KD-R and DON combination on the growth of the CT-2A brain tumour
