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Shachar DB, et al

Therapeutic effects in ameliorating cerebral ischemia-reperfusion injury (CIRI) Cerebral ischemia-reperfusion injury (CIRI) is characterized by disruption of blood supply to the brain, and then the restoration of blood flow, leading to a cascade of pathological mechanisms and eventually result in neuronal damage and death [90]

medRxiv 2022.11.09.22282142 (2023)

Intervertebral disc-derived stem/progenitor cells as a promising cell source for intervertebral disc regeneration

TLR3 detects double-stranded RNA (dsRNA) [21], TLR7 and TLR8 recognise single-stranded RNA (ssRNA) [22], and TLR9 is activated by DNA containing unmethylated CpGs which are abundant in microbial but rare in vertebrate genomes (i.e., 6090% of mammalian CpGs are methylated) [23,24]

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