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Wellness and therapeutic metabolites found in food and botanicals when taken in their natural matrix are generally safe even for chronic consumption, with extremely low toxicity, presenting ease in uptake or breakdown by the body, having low retention, and presenting low potential for physiological dependency [583]

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Finally, by addressing these limitations and following these recommendations, future research can provide more definitive insights into the role of antioxidants in the management of CAP, where the integration of antioxidants into the treatment regimen for CAP holds potential for significantly improving patient outcomes by reducing oxidative stress and inflammation, thereby enhancing the overall effectiveness of conventional therapies

Other ergot derivatives are used as prolactin inhibitors, in the treatment of Parkinsonism, and in cases of cerebrovascular insufficiency [149]

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Proliferation of DU145 prostate cancer cells is inhibited by suppressing insulin-like growth factor binding protein-2