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Copper oxide nanoparticles induce oxidative DNA damage and cell death via copper ion-mediated P38 MAPK activation in vascular endothelial cells

N-acetyl-cysteine (NAC), a derivative of amino acid L-cysteine, is currently used mainly as an antioxidant [15]

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Metabolic reprogramming endows cancer cells with the metabolic plasticity to rewire pathways for bioenergetic and redox homeostasis [3]

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In addition, not all reported connections between mTORC2 and autophagy involve cytoplasmic and nuclear functions of FoxO, as Akt directly phosphorylates and inhibits ULK1 ( In addition to the functions of Akt, inhibition of another member of the AGC kinase family, SGK1, by either genetic and pharmacological means, induces autophagy in vitro and in vivo (Liu et al., 2018