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When you add excessive alcohol consumption to this growing list of factors that deplete antioxidants, the liver struggles to keep up, especially in cases of heavy alcohol consumption

Significant gaps remain, particularly the lack of treatments with adequate safety and true disease-modifying potential capable of addressing key pathological drivers such as neuroinflammation, mitochondrial dysfunction, impaired proteostasis and toxic protein aggregation ( Polygonum cuspidatum ), curcumin ( Curcuma longa ), epigallocatechin gallate (EGCG

"S-Nitrosoglutathione is a substrate for rat alcohol dehydrogenase class III isoenzyme"

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[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Sivak S, Nosal V, Bittsansky M, Dluha J, Dobrota D, Kurca E