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Problems paying for prescription drugs Source: Montero, et al KFF, November 14, 2025 Implications for employers: Plan member interest in GLP-1 medications to treat obesity and cardiometabolic disease is likely to continue to increase

$30B/yr - Novo's GLP-1 revenue for weight-loss & diabetes now beginning to become exposed to generic options

GLP-1 injections work by targeting appetite regulation rather than forcing rapid weight loss

Sustained liraglutide administration for 3 weeks increases urinary sodium excretion independent of changes in ANP or blood pressure in overweight and obese hypertensive patients with type 2 diabetes 22

To minimize discomfort during dose adjustments, patients should be advised to: Eat smaller, more frequent meals rather than large portions Avoid high-fat, greasy, or spicy foods that may exacerbate nausea Stay well-hydrated , particularly if experiencing vomiting or diarrhea Take the injection on the same day each week , ideally when they can rest if needed Avoid lying down immediately after eating to reduce reflux symptoms Timing considerations are important

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