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coli GR in the cytoplasm and chloroplast exhibited enhanced GR activity and tolerance to methyl viologen-mediated oxidative stress (Aono et al., N

Finally, we highlight translational challenges and future directions while emphasizing the considerable promise of integrating AI, biomaterial science, and personalized medicine to advance patient-centric DDS

Intestinal tight junctions (TJ) are responsible for the paracellular trafficking of macromolecules and, therefore, they contribute to the balance between tolerance and immune response to non-self antigens (1)

However, clinical practitioners often recommend a "start low and go slow" approach, particularly for patients with severe chronic illness who may be highly sensitive to new supplements or prone to detoxification reactions (Herxheimer reactions)

The biological mechanismssuch as reducing oxidative stress, inflammation, and modulating gut microbiotaare promising, but the safety profile in very young children or for long-term use requires further exploration