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Novo Nordisk announced that its rebranded and reformulated oral GLP-1 medication, formerly known as Rybelsus, is now available in the U.S

These medications are recognized as powerful tools, offering unprecedented potential for weight

Rapid weight loss with GLP1 receptor agonists can come at the cost of skeletal muscle, potentially undermining metabolic and functional outcomes

Approved 20 years ago as a treatment for diabetes, GLP-1 drugs have been found also to help patients significantly reduce weight

The Moro orange, known for its deep pigmentation due to a high concentration of anthocyanins, is thought to have originated in Sicily in the early 1800s

The GLP1-RAs vs sodium-glucose cotransporter-2 (SGLT-2) inhibitors cohort included new users of GLP-1 RAs (n=83,464) or SGLT-2 inhibitors (n=78,366), and the GLP1-RAs vs dipeptidyl peptidase-4 (DPP-4) inhibitors cohort included new users of GLP-1 RAs (n=108,322) or DPP-4 inhibitors (n=55,411)