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Melanotan I is a synthetic analogue of -melanocyte-stimulating hormone (-MSH) developed for preclinical study of melanogenesis and photoprotection

doi: 10.1093/femsre/fux048 36 Chaves-OlarteE.FlorinI.BoquetP.PopoffM.von Eichel-StreiberC.ThelestamM

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Congenital giant nevi: clinical and pathological considerations

Indeed, on the one hand chloroquine and bortezomib prevented the lysosomal and proteasomal degradation of LIP, as demonstrated by the abrogation of their effects in cells co-incubated with lysosome or proteasome activators

411 In the latter case, the conjugated enone 10 is prepared by treatment of 9 with perchloric acid in tetrahydrofuran, and its reduction with NaBH 4 affords the hydroxy derivative 6