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The peptide appears to exert pleiotropic biological effects involving modulation of angiogenic signaling, inflammatory mediators, cytoprotective pathways, and cellular migration/proliferation processes

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The reported effect may be linked to increased insulin sensitivity and suppression of leucocytes adhesion to the endothelium and transmigration through inhibition of transcription factor NF-B-mediated production of cytokines and adhesion molecules, in both vascular endothelial and inflammatory cells [58,127]