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Riomet (metformin) is another of the diabetes medications that does not cause hypoglycemia by itself but can exacerbate the issue with sulfonylureas

Dalrymple SN, Lewis SH, Philman S

It also lowers the risk of diabetes-related chronic kidney disease, heart failure, cardiovascular disease, and non-alcoholic fatty liver disease

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Luke Berry MD, a UTHSCSA School of Medicine graduate and former Chief Resident in Emergency Medicine

Additionally, studies in which participants were using opioids or other hormonal therapies that could influence testosterone levels were not considered