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Summary: Copper is an essential element that is vital to our health However, copper levels need to be kept within a normal range, because both excessive copper levels, and copper deficiency can have toxic affects to the body Most Copper comes from our diet, but excessive copper can be ingested from copper pipes used in plumbing, copper-lined cookware, and from industrial sources from inhalation during various mining and welding work Genetic disorders such as Wilson disease and Menkes disease can also cause either excessive accumulation of copper (Wilson), or extreme copper deficiency that results in death (Menkes) Copper has different stable oxidation states, so it is widely used in vivo in different redox reactions

Sanderson SM, Gao X, Dai Z, Locasale JW

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Sci Adv 9(28):eadh1403 Rafie F, Rajizadeh MA, Shahbazi M, Pourranjbar M, Nekouei AH, Sheibani V, Peterson D (2023) Effects of voluntary, and forced exercises on neurotrophic factors and cognitive function in animal models of Parkinsons disease

These findings highlight why NRF2 support is more than just antioxidant helpits a cornerstone of cellular survival and recovery under toxic stress

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