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Eur Neuropsychopharmacol

V., Bowyer, M

MASLD is commonly recognized as the liver-related aspect of MS, exacerbates the complications associated with the syndrome

Carnitine secreted by TAMs activates CPT1A/c-Myc positive feedback loop, enhances the antioxidant capacity of cells through the Nrf2/GPX4 pathway, and limits the production of polyunsaturated fatty acids by downregulating the expression of ACSL4

Another mutation deletes a small section of the HADH gene, which likely leads to a truncated enzyme that is again unstable

[DOI] [PubMed] [Google Scholar] 94.Crha I, Hruba D, Ventruba P, Fiala J, Totusek J, Visnova H