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Reagents Dulbeccos Modified Eagle Medium (DMEM) including 4.5g/L glucose, L-glutamine, and sodium pyruvate was purchased from Corning (Mediatech, Inc., Manassas, VA) to culture mammalian cells

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However, peptide therapy offers the advantage of extended treatment duration (daily dosing over weeks) versus the single or limited injection approach of PRP

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Healthcare providers often need to reduce the doses of these concurrent antidiabetic medications when starting semaglutide therapy, with subsequent adjustments based on glucose monitoring results and clinical response