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The mechanism appears to be interference with erythropoiesis

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[8] [11] Whereas most of the GLUD1-GTP interactions are via - and -phosphate interactions, there are specific interactions with E346 and K343 that favour guanosine over adenosine

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Journal of Biophotonics 14 (2021) 202000295

For quantitative assessment of cells, a segmentation mask was generated based on the staining for CD45 and nuclei (Propidiumiodide), which was then used to extract singlecell expression data from images of all measured markers (Fig EV1)