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CBS activity increases the flux via the transsulfuration pathway, which leads to GSH production, which becomes oxidized and depleted during oxidative stress

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cerevisiae strains ABC 1144 (WT) and ABC 1230 (HGT1 cells) are derived from YPH499 (MAT ura352 leu2 1 lys2801 his3 200 trp163 ade2101 ) and carry an integrated URA3 cassette or TEF HGT1 , respectively (Srikanth et al , 2005)

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