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Consequently, it has demonstrated promise therapeutic efficacy in the treatment of cardiovascular illnesses

Clinical trials comparing the two have shown that while both can be effective for managing joint symptoms, they work in very different ways

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The authors found that the bis(tert-butyl-SATE)-PMEA analog retained similar activity to the bis(POM) compound in cells, but saw a half-life increase of over 50-fold in human serum, suggesting the bis(SATE) prodrug may have better in vivo efficacy [40]

doi: 10.1111/j.1365-2869.2004.00429.x

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