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N Engl J Med 333:541 549

Lipid-induced glucose intolerance is driven by impaired glucose kinetics and insulin metabolism in healthy individuals
PK/PD linkage - Controlled human supplementation trials have demonstrated dose-dependent induction of Nrf2 target genes (HO-1, NQO1) in peripheral blood mononuclear cells and reduced selected inflammatory biomarkersproviding mechanistic PD endpoints that can be used to establish pharmacologically active exposure levels for future infectionadjunct trials

Detoxifies Organophosphate Pesticides: Organophosphates were developed in the 1940s as highly toxic biological warfare agents
