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Interestingly, parallel studies in receptor-deficient models still observed apparent weight changes, indicating that additional pathways, such as energy expenditure or fat oxidation, may be involved

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The signal that targeting amylin could preserve lean mass during weight loss a key question about GLP-1 drugs has so far been from animal studies, Drucker pointed out, leading him to question whether that result would bear out in human studies

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J., Hsu, C
