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These properties make GDC a novel and ideal candidate for transiently inducing a leaky, infant-like epithelial phenotype, a previously unexplored approach for modeling early-life gut barrier function in vitro

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It was recently shown that murine tolDCs, generated through ablation of the transcriptional regulator Nuclear Receptor Corepressor 1 (NCoR1), meet a portion of their increased energy needs through enhanced FAO and a subsequent increase in oxygen consumption