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The implications of this in people with Down syndrome need additional study

Ethics declarations Ethics approval Animal care and procedures were conducted according to the guidelines approved by the French Ethical Committee (decree 87 to 848) and by the European Community directive 86 to 609-EEC

Importantly, different stress paradigms can have differential effects on CRH and AVP

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doi: 10.3389/fimmu.2020.00108 [DOI] [PMC free article] [PubMed] [Google Scholar] 82

Duration: Lasts 12-24 months (may require touch-ups)