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These locations are compatible with the enzymes functions: GS produces glutamine for the synthesis of cytoplasmic proteins and nucleotides, whereas GLS catalyses glutamine conversion to glutamate as an important step to the tricarboxylic acid cycle (TCA, also known as the Krebs cycle) entry at 2-oxoglutarate as an energy source or source of metabolic intermediates [3]

Folate Administration Reduces Circulating Homocysteine Levels in NIDDM Patients on Long-Term Metformin Treatment. Journal of Internal Medicine, vol

In addition, glucocorticoids have been found to indirectly increase mitochondrial respiration by inhibiting glycolytic activity

444 Ketamine also potentiates cholesterol transport from astrocytes to neurones, thus stimulating synaptogenesis and morphological plasticity

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doi: 10.1177/20503121211034366