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About this article Cite this article Gu, Ym., Yuan, Qn., Li, X
doi: 10.1016/j.jff.2021.104504

Thus, the macrophage-based strategy for drug delivery harnesses the prolonged circulation time, abundant surface receptors, and active targeting ability of macrophages under specific phenotype

Pannexin-1 channels are increasingly recognized as conduits for ATP release, and experimental blockade of Panx1 has been shown to attenuate peripheral inflammatory pain, underscoring their contribution to nociceptive amplification when inflammation is present [43,45]

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