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The molecular docking study showed that 55 and 56 made a hydrogen bond with the Arg880 residue via the tetrazole ring, as well as another hydrogen bond with Ser876
cerevisiae D7 yeast cells demonstrating a 70% decrease in cell survival compared to the control

[DOI] [PubMed] [Google Scholar] 62.Yan F., Chen X., Zheng X

It does this primarily by suppressing vasopressin production, which in turn makes your kidneys behave as though your body has too much water - resulting in the production of far more urine than normal

Cell Mol Life Sci (2016) 73(1112):2195209

Serotonin Syndrome Risk: Combining SAMe with other serotonergic medicationssuch as SSRIs, SNRIs, MAOIs, tricyclic antidepressants, or supplements like 5-HTPcarries a risk of serotonin syndrome
