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Folic acid increased NADPH level through MTHFD1 to alleviate Ang II-induced vascular aging To further determine whether MTHFD1 mediates the anti-aging effects of FA in vivo, we constructed adeno-associated virus (AAV) containing MTHFD1 shRNA (AAV-shM1) driven by the EC-specific Tie promoter and a negative control construct (AAV-NC)
Noncoding RNA Res

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