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Current evidence suggests GLP-1 drugs like semaglutide do not directly harm sperm production, though weight loss itself can improve hormonal markers and fertility outcomes

Semaglutide injection is a GLP-1 treatment option that may be considered for eligible patients as part of a provider-guided medical weight loss program

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While there was an explosion in the use of GLP-1 drugs in 2025, two pharmaceutical giants are preparing to debut their oral options in 2026