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Gordon, M., Sinopoulou, V., Grafton-Clarke, C

TDP-43 is usually found in the nucleus, but in many cases of ALS it accumulates in the cytoplasm (TDP-43 proteopathy) (Thakur et al

Repairing this intricate, high-stress network is a formidable challenge

Researchers tracking how this evidence base matures can compare it with the companion assessment of whether current research supports cagrilintides role in lowering stroke risk, which weighs a similarly early evidence base for a different endpoint

Doctors don't routinely test for vitamin B12 levels, so vitamin B12 deficiency can go unnoticed

[5] In essence, it releases the brake on the pituitary, causing a surge in the patients own GH output