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In conclusion, riboflavin is a potential neuroprotective agent affecting a wide range of neurological disorders exemplified by PD, a disorder of neurodegeneration, and migraine headache, a disorder of pain

doi: 10.2174/0929867324666161118125827 3 PerlmutterDHColeFSKilbridgePRossingTHColtenHR

Ten genes were identified as important regulators of this process, including ferredoxin 1 ( FDX1 ), lipoic acid synthetase ( LIAS ), lipoyltransferase 1 ( LIPT1 ), dihydrolipoamide dehydrogenase ( DLD ), DLAT , pyruvate dehydrogenase E1 subunit alpha 1 ( PDHA1 ), pyruvate dehydrogenase E1 subunit beta ( PDHB ), metal regulatory transcription factor 1 ( MTF1 ), glutaminase ( GLS ), and cyclin dependent kinase inhibitor 2 A ( CDKN2A )
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The synergistic targeting of NO and gasotransmitter pathways, such as H 2 S, represents an exciting frontier in developing robust anti-cancer strategies for CRC

Govoni, S., Politi, P
