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We think that our proposals could lead to a significant reduction in smoking-related deaths perhaps down to just 100 annually." The proposal also suggests that tobacco smoke should be treated as a carcinogenic substance, and that it should be restricted in a similar way to other known carcinogens, because of the known effects of passive smoking

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Ingested compounds that undergo first pass metabolism could be less active than inhaled compounds, which would have direct access to the bloodstream without being metabolized first

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