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The metabolite 4-OH-E exhibits direct genotoxicity by inducing DNA strand breaks or base oxidation

10.1016/j.bbi.2020.03.014 82

10.1016/bs.apcsb.2019.12.001 306 YaacoubC.WehbeR.RoufayelR.FajlounZ.CoutardB

More studies need to be conducted to test whether repeated dosing could help the drug penetrate further over time

For example, some people are sensitive to smells such as pesticides or solvents, causing headaches, sinus drainage, joint pain, and more

[DOI] [PMC free article] [PubMed] 20.Cotler J, Holtzman C, Dudun C, Jason LA
