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Although it has been the subject of scientific study for decades, it has not received formal approval as a pharmaceutical agent and is not recognized for clinical use

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Therefore, developing a comprehensive therapeutic platform capable of spatiotemporal ROS scavenging, regulation of macrophage polarization, and enhancement of angiogenesis and cell proliferation represents a critical research focus for improving clinical outcomes in chronic diabetic wound management

Heavy metals are implausible in WFI + BA and were absent

doi: 10.1111/j.1600-051x.1997.tb00760.x

Lancet (London, England) 397 , 22842303