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Gastrointestinal symptoms: Nausea, diarrhoea, or mild abdominal discomfort may occur

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Third, select node-specific therapy tailored to that map (e.g., NOX isoform modulation, RET tempering and mitochondrial quality control, UPR^ER tuning, iron/ferroptosis control, NOS re-coupling, RSS support) and co-prescribe lifestyle measures (structured exercise, nutrition, sleep/circadian alignment and exposure control) that reset redox tone without erasing adaptive cues (Meng et al

Indeed, MetS, prevalent among obese individuals, often manifests with glucose intolerance, insulin resistance and dyslipidemia (i.e., hypertriglyceridemia and hypercholesterolemia) (Cornier et al., 2008)

NAD + and NADH are essential cofactors in redox reactions throughout mitochondrial metabolism that maintain redox homeostasis [24, 25]

Elevated insulin levels, along with increased androgen production, interfere with the normal growth and maturation of ovarian follicles, resulting in impaired follicular development and the characteristic symptoms of PCOS