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The needles open temporary channels through the stratum corneum into the upper dermis

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[6] If this happens, vitamin B 12 deficiency may result in sense loss, loss of sensation in the feet, difficulty walking, poor balance, blurred vision, changes in reflexes, muscle weakness, decreased smell and taste, decreased level of consciousness, mood changes, memory loss, depression, irritability, clumsiness, disorientation, dementia and, in severe cases, psychosis

ACS Nano 16 , 1526115272 (2022)
