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The ribonuclease activity of SAMHD1 is required for HIV-1 restriction

Moreno H, Serrano AL, Santalucia T, et al

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Surface plasmon resonance analyses provide direct evidence of melittins interaction with these critical upstream signaling molecules, with dissociation constants of 4.6 10 -6 M (IKK ), 1.34 10 -9 M (IKK ), and 1.01 10 -9 M (p50), highlighting its specificity and potency (90, 91)

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