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IM administration bypasses first-pass metabolism and can provide a prolonged release into the bloodstream compared to IV bolus injection

This enzyme converts folate into its active form, 5-methyltetrahydrofolate (5-MTHF)

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GeneReviews (19932021)

Using transmission electron microscopy and other methods, we observed typical characteristics of ferroptosis, such as changes in mitochondrial morphology and Fe2 + accumulation
