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Ostojic & Zlatko Ahmetovic (2008) Gastrointestinal Distress After Creatine Supplementation in Athletes: Are Side Effects Dose Dependent?, Research in Sports Medicine, 16:1, 15-22, DOI: 10.1080/15438620701693280 Cooper R, Naclerio F, Allgrove J, Jimenez A

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If after a trial the nausea is debilitating and doesnt lessen, that patient might not continue therapy

Therefore, available data suggest a potential role of 3 PUFA supplementation in muscle anabolism and functionality at least in presence of sarcopenia of ageing