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RNA-based therapeutics strategies targeting KRAS can generally be divided into two categories: direct targeting of KRAS mRNA and indirect modulation of KRAS-associated signaling pathways

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Filamin A binds to various cellular proteins, including trans-membrane receptors and signaling molecules, playing a significant role for embryological development, cell migration and mechanical stress response

Inhibition of fatty acid metabolism ameliorates disease activity in an animal model of multiple sclerosis