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The androgen signature is enhanced by the insulin outputs obtained through the PI3K-AKT-mTOR pathway, and in turn, the symptoms are amplified

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They also boost the healing process by promoting tissue repair and stimulating the production of collagen

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99,100 In diabetic nephropathy, excess GH stimulates glomerular growth, affects the structure and function of the kidney, and is associated with glomerular podocyte dysfunction