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doi: 10.3389/fmed.2019.00167 88 VillarroyaFCereijoRGavalda-NavarroAVillarroyaJGiraltM

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For example, Treg cell-specific deletion of phosphatase and tensin homolog (PTEN) causes the hyperactivation of glycolysis and reduces FoxP3 stability, thereby impairing the suppression of Th1 cell and follicular helper T (Tfh) cell immune responses [153]