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Key companies in the United States e-cigarette market include Imperial Brands PLC, Japan Tobacco Inc., Philip Morris International Inc., British American Tobacco PLC, and Juul Labs Inc

hundreds of billions of dollars annually in medical care and lost productivity

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They should be judged by how they work, what risks they carry, who uses them, and what impact they have on public health

This particular health effect is not only caused by nicotine but it can also be caused by the tobaccos harmful chemicals